Theca externa

The external external layer of the theca folliculi, a connective tissue space, surrounds the follicle in the ovary in the advanced stage of the disease. The external externa arises at the stage of the tertiary follicle, where the connective tissue space is differentiated into the external and internal theca. Theca externa consists of connective tissue, whose cells resemble fibroblasts, and contains large amounts of collagen. During ovulation, the increase in the luteinizing hormone (LH) causes an increase in the cyclic adenosine monophosphate (cAMP), which in turn increases the production of progesterone and prostaglandin F2α (PGF2α). The PGF2α dissolves the contraction of the fine muscle cells of Theca externa, thereby increasing the intrafollicular pressure. This supports the release of the mature egg, or - in dogs - the immature egg at the germinal vesicle stage, together with a decomposition of the plasmine and the collagenase of the follicular wall. Single-level Edit source text Weblinks Edit sourcetext

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