Cataplerotic, also described as cataplerotic, (ancient Greek: κατα-πλέω down) are hot reactions, which mainly belong to anabolic pathways and for which the intermediates are derived from the citrate cycle. In contrast, there are anaplerotic reactions.
Important intermediates for such reactions are citrate (eg cholesterol and fatty acid biosynthesis), succinyl-CoA (for porphyrin biosynthesis), L-malate (for gluconeogenesis), oxaloacetate and ketoglutarate (e.g. For amino acid metabolism, for example) Edit source text
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