Akklimatisation

Acclimatization or acclimatization means the individual physiological adaptation of an organism within its genetic prescriptions to changing environmental factors, whereby this adaptation is itself reversible (reversible). Acclimatization of the altitude in humans

The only way to adapt the human organism to high altitudes is acclimatization. Due to a complex adaptation process, the lack of oxygen supply can be partly compensated at high altitudes. Because of the different ability to hypoxic respiratory drive, the adaptation is different for every human being. The normal subtypical changes are expressed in:

The adaptation process, which takes place in different stages, represents a highly complex process, which has not yet been fully explored. In various adaptation phases, the decreased O2 partial pressure is first compensated by increasing the respiratory and cardiac output volume. This causes a respiratory alkalosis, which the body tries to balance. The alveolar vascular reflex improves the oxygen exchange of alveoli and pulmonary capillaries. In the blood, there is a right shift of the hemoglobin-binding curve, weakened by the respiratory alkalosis. Thus the hematocrit increases sharply, which may worsen the flow properties of the blood and lead to thrombosis. The organism can permanently adapt only at altitudes up to 7000 m (increase in height due to the reduction of the critical oxygen partial pressure by chemosensically activated increase in the respiratory volume); at higher altitudes the reduction of all body functions takes place in the long term.

Characteristics for successful acclimatization are:

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