Silyl enol ether


General structure of a silyl enol ether. Silyl ethers of enol, or silyl enol ethers, in organic chemistry are a class of organic compounds that share a common functional group consisting of an enolate bound by its oxygen to an organosilane group.

Silyl enol ethers are important synthetic intermediates in organic synthesis. Synthesis The trimethylsilyl enol ethers, R2C = CR-OSiMe3 or R2C = CR-OTMS, may be prepared from ketones in the presence of a base, triethylamine under thermodynamic control or LDA and -78 ° C under kinetic control, and chloride of trimethylsilyl. Organic Reactions

Silyl ethers of enol react as nucleophiles in, for example:

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