Scorable Marker

In genetic engineering, a gene is designated as a genetic marker, which, together with the gene of interest, is introduced into the altered organism in order to recognize individuals with a successful genetic modification. In contrast to selectable markers, such as antibiotic resistance, scorable markers are directly recognizable by the phenotype of the gene-modified organism, for example by causing a certain coloration. Scorable markers are mainly used for the selection of multicellular organisms. Edit ApplicationQtext

Example for a scorable marker in plants is the gene "uidA", which encodes the acidic hydrolase β-glucoronidase. This hydrolase enzymatically cleaves, for example, the dye X-Gluc to an insoluble blue CIBr indigo dye. This can be seen with the naked eye. Successful transformations of insects are indicated, for example, via the eye color coded by the scorable marker. Edit source text Weblinks Edit sourcetext

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