Lipohyalinose

Lipohyalinosis is a pathological process on vessel walls of small perforating arteries and arterioles of the brain. The term is used synonymously with "fibrinoid necrosis". Fibrinoid necrosis is caused by the entry of plasma proteins into the vessel wall and occurs more frequently in individuals with hypertension than in those with normal blood pressure. It can lead to the closure of the affected vessel and cause a lacunary infarction. The term "lipohyalinosis" was coined by Charles Miller Fisher, but the term "fibrinoid necrosis" describes the underlying pathological changes more precisely. Edit sourcetext

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